The recent sequencing of the entire genomes of mycoplasma genitalium and m pneumoniae has attracted considerable attention among life scientists to the molecular biology of mycoplasmas the smallest self replicating organismsit appears that we are now much closer to the goal of defining in molecular terms the entire machinery of a self replicating cell. Maniloff andmorowitz ence of more than one distinct cellular form during the organisms life cycle the third generalization is that the smallest known viable mycoplasmas single cells capable of
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